PSB-22034

Catalog No.: A61579
MRGPRX4 Agonist
PSB-22034 is a selective agonist of the MRGPRX4 receptor, demonstrating EC50 values of 11.2 nM in Ca2+ mobilization assays and 30.0 nM in β-arrestin recruitment assays. This compound is valuable for investigating the physiological roles of MRGPRX4 and its involvement in pain, neurogenic inflammation, and other pathological processes. Its precise modulation of MRGPRX4 provides a tool for elucidating receptor functions in various biological contexts.
Grouped product items
Size Price Stock Qty
1mg
$250.00
In stock
5mg
$640.00
In stock
10mg
$1,050.00
In stock
25mg
$2,100.00
In stock
50mg
$3,280.00
In stock
100mg
$5,120.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPSB-22034 is a selective agonist of the MRGPRX4 receptor, demonstrating EC50 values of 11.2 nM in Ca2+ mobilization assays and 30.0 nM in β-arrestin recruitment assays. This compound is valuable for investigating the physiological roles of MRGPRX4 and its involvement in pain, neurogenic inflammation, and other pathological processes. Its precise modulation of MRGPRX4 provides a tool for elucidating receptor functions in various biological contexts.
Product Information
Catalog NumA61579
FormulaC21H25N4O6P
Molecular Weight460.42
CAS Number2768131-22-0
SMILESO=C1C2=C(N(C(N1CC#C)=O)CCCCP(O)(O)=O)N=C(N2)CCC3=CC(OC)=CC=C3
Useful Calculator

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