PSDalpha is an estrogen receptor alpha (ERα) degrader that features a conjugation of a photosensitizer (PS), triphenylamine benzothiadiazole (TB), and 17β-estradiol through an acetylene bond. It demonstrates potent anti-proliferative effects on MCF-7 breast cancer cells. PSDalpha exhibits a maximum absorption wavelength of 465 nm in the visible spectrum, making it suitable for photodynamic therapy applications and studies related to ERα-targeted cancer treatments.
PSDalpha is an estrogen receptor alpha (ERα) degrader that features a conjugation of a photosensitizer (PS), triphenylamine benzothiadiazole (TB), and 17β-estradiol through an acetylene bond. It demonstrates potent anti-proliferative effects on MCF-7 breast cancer cells. PSDalpha exhibits a maximum absorption wavelength of 465 nm in the visible spectrum, making it suitable for photodynamic therapy applications and studies related to ERα-targeted cancer treatments.
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