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PTC-209

Catalog No.: A13826

BMI-1 inhibitor

PTC-209

PTC-209 Chemical Structure

CAS NO. 315704-66-6

PTC-209 is a novel potent and selective BMI-1 inhibitor, targeting the BMI-1 self-renewal machinery with an IC50 of ~0.5 μM.

Availability: In stock

Package Price Qty
5 mg
$75.00
10 mg
$125.00
25 mg
$250.00
10mM * 1mL in DMSO
$100.00
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Biological Activity

PTC-209 is a novel potent and selective BMI-1 inhibitor, targeting the BMI-1 self-renewal machinery with an IC50 of ~0.5 μM.
Targets
BMI-1 (HEK293T cells)
0.5 μM
In vitro DMSO 92 mg/mL (185.78 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.19 mL 100.97 mL 201.94 mL
0.5 mM 4.04 mL 20.19 mL 40.39 mL
1 mM 2.02 mL 10.1 mL 20.19 mL
5 mM 0.4 mL 2.02 mL 4.04 mL

*The above data is based on the productmolecular weight 495.19. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13826
Actions Inhibitor
CAS No. 315704-66-6
Formula C17H13Br2N5OS
M. Wt 495.19
Purity >98%
Synonyms PTC209, PTC 209
SMILES CC1=C(N2C=CC=NC2=N1)C3=CSC(=N3)NC4=C(C=C(C=C4Br)OC)Br
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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