PTK7/β-catenin-IN-1 is a selective inhibitor targeting the PTK7/β-catenin signaling pathway, demonstrating an IC50 of 8.9 μM for PTK7/β-catenin and 56.5 μM for p53/MDM2. This compound shows promise in cancer research, particularly in studies examining the modulation of tumorigenic pathways influenced by β-catenin. Its inhibitory effects provide a valuable tool for investigating the role of PTK7 in cancer progression and therapeutic strategies.
PTK7/β-catenin-IN-1 is a selective inhibitor targeting the PTK7/β-catenin signaling pathway, demonstrating an IC50 of 8.9 μM for PTK7/β-catenin and 56.5 μM for p53/MDM2. This compound shows promise in cancer research, particularly in studies examining the modulation of tumorigenic pathways influenced by β-catenin. Its inhibitory effects provide a valuable tool for investigating the role of PTK7 in cancer progression and therapeutic strategies.
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