Pulrodemstat Methylbenzenesulfonate is a selective, reversible inhibitor of lysine-specific demethylase-1 (LSD1), exhibiting an IC50 of 0.25 nM. This compound demonstrates minimal inhibition of LSD2, monoamine oxidase A, and monoamine oxidase B. Pulrodemstat Methylbenzenesulfonate effectively induces differentiation in acute myeloid leukemia (AML) and small cell lung cancer (SCLC) cells, showcasing significant anticancer activity. Its targeted action positions it as a valuable reagent in cancer research and therapeutic studies.
Pulrodemstat Methylbenzenesulfonate is a selective, reversible inhibitor of lysine-specific demethylase-1 (LSD1), exhibiting an IC50 of 0.25 nM. This compound demonstrates minimal inhibition of LSD2, monoamine oxidase A, and monoamine oxidase B. Pulrodemstat Methylbenzenesulfonate effectively induces differentiation in acute myeloid leukemia (AML) and small cell lung cancer (SCLC) cells, showcasing significant anticancer activity. Its targeted action positions it as a valuable reagent in cancer research and therapeutic studies.
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