Biological Activity
PUN30119, also known as Imidazole ketone erastin (IKE), is a potent, metabolically stable inhibitor of system xc- and inducer of ferroptosis potentially suitable for in vivo applications.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 15.26 mL | 76.32 mL | 152.64 mL |
0.5 mM | 3.05 mL | 15.26 mL | 30.53 mL |
1 mM | 1.53 mL | 7.63 mL | 15.26 mL |
5 mM | 0.31 mL | 1.53 mL | 3.05 mL |
*The above data is based on the productmolecular weight 655.152. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A17232 |
---|---|
Actions | Inhibitor, Modulator |
M. Wt | 655.152 |
Formula | C35H35ClN6O5 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1801530-11-9 |
Synonyms | Imidazole ketone erastin; IKE; Ferroptosis inducer IKE; PUN30119; PUN-30119; PUN 30119; |
SMILES | O=C1N(C2=CC(C(CN3C=NC=C3)=O)=CC=C2OC(C)C)C(CN4CCN(C(COC5=CC=C(Cl)C=C5)=O)CC4)=NC6=C1C=CC=C6 |
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