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$0.00 Biological Activity
PX20606, also known as PX-102, is a FXR agonist. It induces high-density lipoprotein-mediated transhepatic cholesterol efflux in mice and monkeys and prevent atherosclerosis in cholesteryl ester transfer protein transgenic low-density lipoprotein receptor (-/-) mice.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.02 mL | 90.11 mL | 180.23 mL |
| 0.5 mM | 3.6 mL | 18.02 mL | 36.05 mL |
| 1 mM | 1.8 mL | 9.01 mL | 18.02 mL |
| 5 mM | 0.36 mL | 1.8 mL | 3.6 mL |
*The above data is based on the productmolecular weight 554.85. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A16997 |
|---|---|
| Actions | Agonist |
| CAS No. | 1268244-85-4 |
| Formula | C29H22Cl3NO4 |
| M. Wt | 554.85 |
| Solubility | DMSO |
| Purity | >98% |
| Synonyms | PX-20606, PX 20606, PX-102, PX 102, PX10 |
| SMILES | O=C(O)C1=CC=C([[email protected]@H]2[[email protected]@H](C3=CC=C(OCC4=C(C5CC5)ON=C4C6=C(Cl)C=CC=C6Cl)C=C3Cl)C2)C=C1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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