PX20606 trans-isomer

Catalog No.: A16997

FXR agonist

PX20606 trans-isomer

PX20606 trans-isomer Chemical Structure

CAS NO. 1268244-85-4

PX20606, also known as PX-102, is a FXR agonist. It induces high-density lipoprotein-mediated transhepatic cholesterol efflux in mice and monkeys and prevent atherosclerosis in cholesteryl ester transfer protein transgenic low-density lipoprotein receptor (-/-) mice.

Availability: In stock

Package Price Qty
1 mg
$120.00
2 mg
$200.00
5 mg
$400.00
10 mg
$720.00
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Biological Activity

PX20606, also known as PX-102, is a FXR agonist. It induces high-density lipoprotein-mediated transhepatic cholesterol efflux in mice and monkeys and prevent atherosclerosis in cholesteryl ester transfer protein transgenic low-density lipoprotein receptor (-/-) mice.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.02 mL 90.11 mL 180.23 mL
0.5 mM 3.6 mL 18.02 mL 36.05 mL
1 mM 1.8 mL 9.01 mL 18.02 mL
5 mM 0.36 mL 1.8 mL 3.6 mL

*The above data is based on the productmolecular weight 554.85. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16997
Actions Agonist
CAS No. 1268244-85-4
Formula C29H22Cl3NO4
M. Wt 554.85
Solubility DMSO
Purity >98%
Synonyms PX-20606, PX 20606, PX-102, PX 102, PX10
SMILES O=C(O)C1=CC=C([[email protected]@H]2[[email protected]@H](C3=CC=C(OCC4=C(C5CC5)ON=C4C6=C(Cl)C=CC=C6Cl)C=C3Cl)C2)C=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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