Pyrimethamine

Catalog No.: A10763
Pyrimethamine(RP4753) is a medication used for protozoal infections; interferes with tetrahydrofolic acid synthesis from folic acid by inhibiting the enzyme dihydrofolate reductase (DHFR).
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Size Price Stock Qty
50mg
$30.00
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100mg
$45.00
In stock
200mg
$70.00
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500mg
$130.00
In stock
10mM * 1mL in DMSO
$45.00
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription Pyrimethamine(RP4753) is a medication used for protozoal infections; interferes with tetrahydrofolic acid synthesis from folic acid by inhibiting the enzyme dihydrofolate reductase (DHFR).
Cell Research
Cell Line Type Value Description References
Product Information
Catalog Num A10763
Formula C12H13ClN4
Molecular Weight 248.71
CAS Number 58-14-0
SMILES NC1=NC(N)=C(C2=CC=C(Cl)C=C2)C(CC)=N1
Synonyms Pirimecidan; Pirimetamin; RP 4753, RP-4753, RP4753
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 10 mg/mL (40.2 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 40.21 mL 201.04 mL 402.07 mL
0.5 mM 8.04 mL 40.21 mL 80.41 mL
1 mM 4.02 mL 20.1 mL 40.21 mL
5 mM 0.8 mL 4.02 mL 8.04 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

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    C2

    V2

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