QNZ (EVP4593)

Catalog No.: A12748

NF-κB inhibitor

QNZ (EVP4593) Chemical Structure

CAS NO. 545380-34-5

QNZ inhibits the activation of the transcription factor NF-κB and has been used to investigate NF-κB signaling.

Availability: In stock

Package Price Qty
5 mg
$50.00
10 mg
$80.00
25 mg
$150.00
50 mg
$250.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

QNZ inhibits the activation of the transcription factor NF-κB and has been used to investigate NF-κB signaling.
Targets
TNF-α (Jurkat T cells) NF-κB (Jurkat T cells)
7 nM11 nM
In vitro (25°C) DMSO 5 mg/mL (14.02 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% hydroxyethyl cellulose 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.06 mL 140.29 mL 280.58 mL
0.5 mM 5.61 mL 28.06 mL 56.12 mL
1 mM 2.81 mL 14.03 mL 28.06 mL
5 mM 0.56 mL 2.81 mL 5.61 mL

*The above data is based on the productmolecular weight 356.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12748
Actions Inhibitor
M. Wt 356.4
Formula C22H20N4O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 545380-34-5
Synonyms CAY10470, CAY 10470, CAY-10470
SMILES C1=CC=C(C=C1)OC2=CC=C(C=C2)CCNC3=NC=NC4=C3C=C(C=C4)N

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