Quecitinib

Catalog No.: A33283
JAK1/TYK2 Inhibitor
Quecitinib is an orally active dual inhibitor of JAK1 and TYK2, functioning by obstructing their enzymatic activity. This compound exhibits significant biological activity relevant to the modulation of immune responses, making it valuable in research on atopic dermatitis and various autoimmune diseases. Favorable pharmacokinetic properties, along with a safety profile attributed to its metabolism via cytochrome P450 3A, enhance its potential as a therapeutic agent in related studies.
Grouped product items
Size Price Stock Qty
5mg
$515.00
In stock
10mg
$840.00
In stock
25mg
$1,555.00
In stock
50mg
$2,420.00
In stock
100mg
$3,720.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionQuecitinib is an orally active dual inhibitor of JAK1 and TYK2, functioning by obstructing their enzymatic activity. This compound exhibits significant biological activity relevant to the modulation of immune responses, making it valuable in research on atopic dermatitis and various autoimmune diseases. Favorable pharmacokinetic properties, along with a safety profile attributed to its metabolism via cytochrome P450 3A, enhance its potential as a therapeutic agent in related studies.
Product Information
Catalog NumA33283
FormulaC17H20N6O
Molecular Weight324.38
CAS Number2416858-84-7
SMILESO[C@H](C)C1=NC2=CN=C(NC=C3)C3=C2N1N4CCC(CC#N)CC4
SynonymsQY201
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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