(R)-AM-1638

Name: (R)-AM-1638
Brand: Adooq Bioscience
SKU: A60362
Rating: 5 (288 reviews)

Catalog No.: A60362

GPR40 Agonist

(R)-AM-1638 is a R-isomer of AM-1638 and acts as a full agonist of the GPR40 receptor, exhibiting an EC50 of 0.16 μM. This compound plays a significant role in mediating glucose-dependent insulin secretion and is of particular interest in diabetes research. Its selectivity for GPR40 positions it as a valuable tool for studying metabolic disorders and potential therapeutic interventions.

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Biological Activity

Description	(R)-AM-1638 is a R-isomer of AM-1638 and acts as a full agonist of the GPR40 receptor, exhibiting an EC50 of 0.16 μM. This compound plays a significant role in mediating glucose-dependent insulin secretion and is of particular interest in diabetes research. Its selectivity for GPR40 positions it as a valuable tool for studying metabolic disorders and potential therapeutic interventions.

Product Information

Catalog Num	A60362
Formula	C33H35FO4
Molecular Weight	514.63
CAS Number	1142222-18-1
SMILES	FC1=CC=C(OC)C=C1C2=C(C3=CCCC3(C)C)C=C(C=C2)COC4=CC([C@@H](C5CC5)CC(O)=O)=CC=C4

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