(R)-GNE-140

Catalog No.: A21863

LDHA inhibitor

(R)-GNE-140

(R)-GNE-140 Chemical Structure

CAS NO. 2003234-63-5

(R)-GNE-140 is a potent lactate dehydrogenase A (LDHA) inhibitor, with IC50s of 3 nM and 5 nM for LDHA and LDHB, respectively; (R)-GNE-140 is 18-fold more potent than S enantiomer.

Availability: In stock

Package Price Qty
1 mg
$108.00
5 mg
$324.00
10 mg
$552.00
50 mg
$1,656.00
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Biological Activity

(R)-GNE-140 is a potent lactate dehydrogenase A (LDHA) inhibitor, with IC50s of 3 nM and 5 nM for LDHA and LDHB, respectively; (R)-GNE-140 is 18-fold more potent than S enantiomer.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.04 mL 100.19 mL 200.38 mL
0.5 mM 4.01 mL 20.04 mL 40.08 mL
1 mM 2 mL 10.02 mL 20.04 mL
5 mM 0.4 mL 2 mL 4.01 mL

*The above data is based on the productmolecular weight 499.04. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21863
Actions Inhibitor
M. Wt 499.04
Formula C25H23ClN2O3S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 2003234-63-5
Synonyms GNE140, GNE 140
SMILES O=C1N[[email protected]@](C2=CSC=C2)(C3=CC=C(N4CCOCC4)C=C3)CC(O)=C1SC5=CC=CC=C5Cl

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