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(R)-Nedisertib ((R)-M3814) is a less active R-enantiomer of Nedisertib, with an IC50 in the range of 7-30 nM for DNA-PK.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.75 mL | 103.75 mL | 207.51 mL |
| 0.5 mM | 4.15 mL | 20.75 mL | 41.5 mL |
| 1 mM | 2.08 mL | 10.38 mL | 20.75 mL |
| 5 mM | 0.42 mL | 2.08 mL | 4.15 mL |
*The above data is based on the productmolecular weight 481.91. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21375 |
|---|---|
| CAS No. | 1637542-32-5 |
| Formula | C24H21ClFN5O3 |
| M. Wt | 481.91 |
| Solubility | DMSO |
| Purity | >98% |
| Synonyms | (R)-M3814, M 3814, M-3814 |
| SMILES | ClC1=C([[email protected]@H](O)C2=NN=C(OC)C=C2)C=C(C3=C4C=CC(N5CCOCC5)=CC4=NC=N3)C(F)=C1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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