(R)-PD 0325901CL

Catalog No.: A65820
MEK Inhibitor
(R)-PD 0325901CL is a selective inhibitor of mitogen-activated protein kinase kinase (MEK), a key regulator in the MAPK signaling pathway. This compound demonstrates significant antitumor activity, effectively inhibiting the proliferation of cancer cells both in vitro and in vivo. Its utility in cancer research makes it a valuable reagent for studies focused on targeted therapies and the elucidation of MEK-related mechanisms in oncogenesis.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(R)-PD 0325901CL is a selective inhibitor of mitogen-activated protein kinase kinase (MEK), a key regulator in the MAPK signaling pathway. This compound demonstrates significant antitumor activity, effectively inhibiting the proliferation of cancer cells both in vitro and in vivo. Its utility in cancer research makes it a valuable reagent for studies focused on targeted therapies and the elucidation of MEK-related mechanisms in oncogenesis.
Product Information
Catalog NumA65820
FormulaC16H14ClF2IN2O4
Molecular Weight498.65
CAS Number1003216-77-0
SMILESO=C(NOC[C@H](O)CO)C1=CC=C(F)C(F)=C1NC2=CC=C(I)C=C2Cl
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