(R,R)-THC

Catalog No.: A85156
ERα Agonist/ERβ Antagonist
(R,R)-THC is a selective estrogen receptor alpha (ERα) agonist and estrogen receptor beta (ERβ) antagonist, exhibiting Ki values of 9.0 nM for ERα and 3.6 nM for ERβ. This compound demonstrates higher binding affinity for ERβ than for ERα, with respective values of 25 nM and 3.6 nM. (R,R)-THC is valuable for research applications exploring estrogen receptor signaling pathways and investigating the differential roles of ERα and ERβ in various biological processes.
Grouped product items
Size Price Stock Qty
5mg
$490.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
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Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(R,R)-THC is a selective estrogen receptor alpha (ERα) agonist and estrogen receptor beta (ERβ) antagonist, exhibiting Ki values of 9.0 nM for ERα and 3.6 nM for ERβ. This compound demonstrates higher binding affinity for ERβ than for ERα, with respective values of 25 nM and 3.6 nM. (R,R)-THC is valuable for research applications exploring estrogen receptor signaling pathways and investigating the differential roles of ERα and ERβ in various biological processes.
Product Information
Catalog NumA85156
FormulaC22H24O2
Molecular Weight320.42
CAS Number221368-54-3
SMILESOC(C=C1C[C@H]2CC)=CC=C1C3=C2C4=C(C=C(O)C=C4)C[C@H]3CC
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

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