(R,R)-VVD-118313 is a selective inhibitor of Janus kinase 1 (JAK1), targeting its role in cytokine signaling and trans-phosphorylation. This compound demonstrates significant potential in cancer research by modulating JAK1-mediated pathways. Additionally, (R,R)-VVD-118313 serves as a click chemistry reagent, featuring an alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing compounds, further expanding its utility in chemical biology applications.
(R,R)-VVD-118313 is a selective inhibitor of Janus kinase 1 (JAK1), targeting its role in cytokine signaling and trans-phosphorylation. This compound demonstrates significant potential in cancer research by modulating JAK1-mediated pathways. Additionally, (R,R)-VVD-118313 serves as a click chemistry reagent, featuring an alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing compounds, further expanding its utility in chemical biology applications.
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