France
You have no items in your shopping cart.
Publications citing Adooq Products
Chemical Information
| Catalog Num | A13111 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 356.78 |
| Formula | C18H14ClFN4O |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 882531-87-5 |
| Synonyms | R-1530, R 1530 |
| SMILES | CC1=C2C(=NC3=CC(=C(C=C3C(=N2)C4=CC=CC=C4Cl)F)OC)NN1 |
Description |
R1530 is a pyrazolobenzodiazepine small molecule with potential antiangiogenesis and antineoplastic activities. R1530 is also a mitosis-angiogenesis inhibitor (MAI) that inhibits multiple receptor tyrosine kinases involved in angiogenesis, such as vascular endothelial growth factor receptor (VEGFR)-1, -2, -3, platelet-derived growth factor receptor (PDGFR) beta? FMS-like tyrosine kinase (Flt)-3, and fibroblast growth factor receptor (FGFR) -1, -2. | |||||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.03 mL | 140.14 mL | 280.28mL |
| 0.5 mM | 5.61 mL | 28.03 mL | 56.06 mL |
| 1 mM | 2.8 mL | 14.01 mL | 28.03 mL |
| 5 mM | 0.56 mL | 2.8 mL | 5.61 mL |
*The above data is based on the productmolecular weight 356.78. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Ordering online
To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.
To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.
When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards. We will then liaise with you or your purchasing department to confirm the order.
Found your products but not ready to order?
Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.
Ordering offline
You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order. Our contact details are:
- Tel: 866-930-6790
- Fax: 323-606-8156
- Email: [email protected]
We require the following information to process your order:
- The catalog number for each product.
- Your email address or fax number.
- Your name and telephone number.
- Shipping address and billing address.
- Purchase order numbers.
Similar product(s)
Special Price Starting at:
€266.00
FIIN-3 is a potent, selective, irreversible and the next-generation covalent FGFR inhibitor. ...
Special Price Starting at: €266.00
Special Price Starting at:
€42.75
Regorafenib (BAY 73-4506) is a multikinase inhibitor with IC50 of 17, 40 and 69 nM c-KIT, VEGFR2, B-Raf. Regorafenib (BAY 73-4506) is an orally bioavailable multikinase inhibitor targeting both the tu ...
Special Price Starting at: €42.75
Special Price Starting at:
€142.50
XL647 is an orally bioavailable small-molecule RTK inhibitor that binds to and inhibits several tyrosine receptor kinases that play major roles in tumor cell proliferation and tumor vascularization, i ...
Special Price Starting at: €142.50
Special Price Starting at:
€237.50
BMS-690514 is a potent and selective inhibitor of epidermal growth factor receptor (EGFR), HER2, and HER4, as well as the VEGF receptor kinases. ...
Special Price Starting at: €237.50
Special Price Starting at:
€209.00
TG 100572 is VEGFR2 and Src kinase inhibitor. ...
Special Price Starting at: €209.00
Special Price Starting at:
€34.20
Tivozanib (AV-951) is an oral VEGF receptor tyrosine kinase inhibitor that is designed to inhibit all three VEGF receptors. ...
Special Price Starting at: €34.20
Special Price Starting at:
€42.75
BGJ398 is a potent and selective inhibitor with potential antiangiogenic and antineoplastic activities of fibroblast growth factor receptor (FGFR) tyrosine kinases 1, 2, 3 and 4 (with IC50 values of ...
Special Price Starting at: €42.75
Special Price Starting at:
€128.25
(-)-Catechin gallate is an antioxidant constituent of green tea. At uM concentrations, inhibits VEGF-induced tyrosine phosphorylation. ...
Special Price Starting at: €128.25
Special Price Starting at:
€213.75
N-desethyl sunitinib is a major and pharmacologically active metabolite of sunitinib, which is potent, ATP-competitive VEGFR, PDGFRβ and KIT inhibitor (Ki values are 2, 9, 17, 8 and 4 nM for VEGFR -1 ...
Special Price Starting at: €213.75
Special Price Starting at:
€76.95
NVP-BAW2881 is a potent and selective VEGFR inhibitor (vascular endothelial growth factor receptor tyrosine kinase inhibitor) with activity to inhibit chronic and acute skin inflammation. ...
Special Price Starting at: €76.95
Special Price Starting at:
€76.95
Crenolanib (CP-868596) is an orally bioavailable, selective small molecule inhibitor of the PDGFR tyrosine kinase, inhibiting both PDGFRA and PDGFRB at picomolar concentrations. ...
Special Price Starting at: €76.95
Special Price Starting at:
€42.75
Ki8751 is a cell-permeable quinolyloxyphenyl-urea compound that acts as a Flk-1 (VEGFR-2)-selective inhibitior in both cell-based and cell-free assays. ...
Special Price Starting at: €42.75
Special Price Starting at:
€76.95
Toceranib is a kinase inhibitor with both antitumor and antiangiogenic activity through inhibition of KIT, vascular endothelial growth factor receptor 2, and PDGFRβ.
...
Special Price Starting at: €76.95
Special Price Starting at:
€34.20
Cediranib (AZD2171) s a potent inhibitor of vascular endothelial growth factor (VEGF) receptor tyrosine kinases. ...
Special Price Starting at: €34.20
Special Price Starting at:
€85.50
Telatinib (BAY 57-9352) is an orally available, small-molecule inhibitor of vascular endothelial growth factor receptors 2 and 3 (VEGFR-2/-3) and platelet-derived growth factor receptor β tyrosine ki ...
Special Price Starting at: €85.50
Special Price Starting at:
€102.60
CP 673451 is a potent PDGFR-β inhibitor with an IC50 of 1 nM.
...
Special Price Starting at: €102.60
Special Price Starting at:
€180.50
E-3810 is a potent and selective dual inhibitor of VEGF and FGF receptors with IC50 values of 7 nM, 25 nM, 10 nM, 17.5 nM and 82.5 nM for VEGFR-1, VEGFR-2, VEGFR-3, FGFR-1 and FGFR-2, respectively. ...
Special Price Starting at: €180.50
Special Price Starting at:
€95.00
BMS-817378 is a novel prodrug of the dual Met/VEGFR-2 inhibitor BMS-794833. ...
Special Price Starting at: €95.00
Special Price Starting at:
€85.50
Brivanib alaninate (BMS-582664) is a dual tyrosine kinase inhibitor of VEGFR and FGFR signaling. ...
Special Price Starting at: €85.50
Special Price Starting at:
€59.85
Aurora kinase/VEGFR 2 inhibitor CYC116 inhibits Aurora kinases A and B and vascular endothelial growth factor receptor 2 (VEGFR2), resulting in disruption of the cell cycle, rapid cell death, and the ...
Special Price Starting at: €59.85
Special Price Starting at:
€34.20
Motesanib (AMG706) is a multikinase inhibitor that selectively targets VEGF receptors, platelet-derived growth factor receptors (PDGFRs), and Kit receptors with IC?? values of 2 nM (VEGFR1), 3 nM (VEG ...
Special Price Starting at: €34.20
Special Price Starting at:
€114.00
AC710 Mesylate is a potent, selective PDGFR-family kinases inhibitor with Kd values of 0.6 nM/1.0 nM/1.3 nM/1.0 nM for FLT3/KIT/PDGFRα/PDGFRβ respectively. ...
Special Price Starting at: €114.00
Special Price Starting at:
€34.20
Axitinib is a small molecule tyrosine kinase inhibitor,which inhibits multiple targets, including VEGFR-1, VEGFR-2, VEGFR-3, platelet derived growth factor receptor (PDGFR), and cKIT (CD117). ...
Special Price Starting at: €34.20
Special Price Starting at:
€42.75
AZD4547 is a potent, selective and orally active pan-FGFR inhibitor, with IC50s of 0.2, 2.5, 1.8 and 165 nM for FGFR1, 2, 3 and 4, respectively. ...
Special Price Starting at: €42.75
Special Price Starting at:
€85.50
ZM 323881 is a potent and selective inhibitor of the kinase activity of the human vascular endothelial growth factor receptor 2 (VEGFR2/KDR). ...
Special Price Starting at: €85.50
Special Price Starting at:
€104.50
Debio-1347 is an orally bioavailable inhibitor of the fibroblast growth factor receptor subtypes 1 (FGFR-1), 2 (FGFR-2) and 3 (FGFR-3), with potential antineoplastic activity. ...
Special Price Starting at: €104.50
Special Price Starting at:
€94.05
BLU9931 is the first selective small molecule inhibitor of FGFR4 with IC50 of 3 nM; less potent for FGFR1/2/3(IC50> 150 nM), ...
Special Price Starting at: €94.05
Special Price Starting at:
€42.75
Orantinib (TSU-68, SU6668) has greatest potency against PDGFR autophosphorylation with Ki of 8 nM in a cell-free assay, but also strongly inhibits Flk-1 and FGFR1 trans-phosphorylation, little activit ...
Special Price Starting at: €42.75
Special Price Starting at:
€34.20
Pazopanib is a potent and selective multi-targeted receptor tyrosine kinase inhibitor of VEGFR-1, VEGFR-2, VEGFR-3, PDGFR-a/β, and c-kit that blocks tumor growth and inhibits angiogenesis. ...
Special Price Starting at: €34.20
Special Price Starting at:
€59.85
SU 5416 is an inhibitor of vascular endothelial growth factor receptor (VEGFR) that also inhibits other tyrosine kinases KIT, MET, FLT3 and RET. ...
Special Price Starting at: €59.85
Keywords:buy R1530 | R1530 Supplier | purchase R1530 | R1530 cost | R1530 manufacturer | order R1530 | R1530 distributor | buy 882531-87-5| 882531-87-5 Supplier | purchase 882531-87-5 | 882531-87-5 cost | 882531-87-5 manufacturer | order 882531-87-5 | 882531-87-5 distributor
We Using Safe Payments:
