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Raf265 derivative is a derivative of Raf265 that is an oral, highly selective RAF and VEGFR kinase inhibitor with IC50 of of 5 to 10 μM.
Targets
| In vitro | DMSO | 101 mg/mL (200.24 mM) | |
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | 101 mg/mL (200.24 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.83 mL | 99.13 mL | 198.26 mL |
| 0.5 mM | 3.97 mL | 19.83 mL | 39.65 mL |
| 1 mM | 1.98 mL | 9.91 mL | 19.83 mL |
| 5 mM | 0.4 mL | 1.98 mL | 3.97 mL |
*The above data is based on the productmolecular weight 504.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Technical Details
| Catalog Num | A10774 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 504.4 |
| Formula | C23H14F6N6O |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | N/A |
| Synonyms | N/A |
| SMILES | C1=CC(=CC=C1C(F)(F)F)NC2=NC3=C(N2)C=C(C=C3)OC4=CC(=NC=C4)C5=NC=C(N5)C(F)(F)F |
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