Ramelteon is a melatonin receptor agonist with both high affinity for melatonin MT1 (IC50 =28.5 ?? 8.55 pM)and MT2 (20.1 ?? 9.25 pM)receptors and selectivity over the MT3 receptor.
Ramelteon is a melatonin receptor agonist with both high affinity for melatonin MT1 (IC50 =28.5 ?? 8.55 pM)and MT2 (20.1 ?? 9.25 pM)receptors and selectivity over the MT3 receptor.
Targets
Target
Value
Product Information
Catalog Num
A10777
Formula
C16H21NO2
Molecular Weight
259.3
CAS Number
196597-26-9
SMILES
CCC(=O)NCC[C@@H]1CCC2=C1C3=C(C=C2)OCC3
Synonyms
Rozerem, TAK-375, TAK375
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Solubility
In vitro (25°C)
DMSO
47 mg/mL (181.22 mM)
Water
Insoluble
Ethanol
47 mg/mL (181.22 mM)
In vivo
0.5% methylcellulose
28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula: