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Rapamycin (Sirolimus)

Catalog No.: A10782
mTOR Inhibitors
Adooq's Rapamycin (Sirolimus) has been cited by 15 publications
Rapamycin (Sirolimus) prevents activation of T cells and B-cells by inhibiting their response to interleukin-2 (IL-2).
Rapamycin (Sirolimus)
Grouped product items
Product Name Price Stock Qty
Rapamycin 5mg
$40.00
In stock
Rapamycin 50mg
$55.00
In stock
Rapamycin 100mg
$70.00
In stock
Rapamycin (Sirolimus) 10mM * 1mL in DMSO
$50.00
In stock
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Adooq Products cited in reputable paper
Adooq's Rapamycin (Sirolimus) has been cited by 15 publications
  • Yudong Li, .et al. , J Polym Sci, 2024, 62:2215-2230
  • Ross van de Weterin, .et al. , Glia, 2024, Jun 20 PMID: 38899723
  • Yuanqin Zhang, .et al. , Cancers (Basel), 2023, Dec 2;15(23):5691 PMID: 38067394
  • Amnon Wittenstein, .et al. , PLoS Biol, 2023, Nov 9;21(11):e3002355 PMID: 37943958
  • Bopei Cui, .et al. , Signal Transduct Target Ther, 2023, Sep 25;8(1):366 PMID: 37743418
  • Hideki Kawasaki, .et al. , J Insect Physiol, 2023, Mar;145:104476 PMID: 36623750
  • R Mahalakshmi, .et al. , Mol Biol Rep, 2022, Jan;49(1):463-476 PMID: 34739690
  • Yusuke Murase, .et al. , Oncol Rep, 2022, Apr;47(4):61 PMID: 35088890
  • Zhichao Wu, .et al. , Cells, 2021, Oct 27;10(11):2912 PMID: 34831135
  • Matthew A Schaller, .et al. , JCI Insight, 2021, Sep 22;6(18):e148003 PMID: 34357881
  • Matthew A. Schaller, .et al. , bioRxiv, 2021, January 21
  • Ashley VanCleave, .et al. , Oncotarget, 2020, Jul 7; 11(27): 2597-2610 PMID: 32676162
  • Y Huang, .et al. , Experimental and Therapeutic Medicine, 2020, 20(2), 736-747 PMID: 32742319
  • Takuya Hirao, .et al. , Cancer Sci, 2018, Jan; 109(1): 121-131 PMID: 29121435
  • Ya-Hui Chen, .et al. , J Diabetes Res, 2016, 2016: 1828071 PMID: 28004006
    • Biological Activity
    Discription Rapamycin (Sirolimus) prevents activation of T cells and B-cells by inhibiting their response to interleukin-2 (IL-2).
    Targets
    Target Value
    Product Information
    Catalog Num A10782
    Formula C51H79NO13
    Molecular Weight 914.2
    CAS Number 53123-88-9
    SMILES C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)O)C)/C)O)OC)C)C)/C)OC
    Synonyms Rapamune
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Solubility
    In vitro (25°C) DMSO 18 mg/mL (19.68 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 2% DMSO+30% PEG 300+5% Tween 80+ddH2O 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 10.94 mL 54.69 mL 109.39 mL
    0.5 mM 2.19 mL 10.94 mL 21.88 mL
    1 mM 1.09 mL 5.47 mL 10.94 mL
    5 mM 0.22 mL 1.09 mL 2.19 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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    PI3K/Akt/mTOR > mTOR
    Immunology & Inflammation > Immunosuppressants
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