Rapamycin (Sirolimus)

Rapamycin (Sirolimus) prevents activation of T cells and B-cells by inhibiting their response to interleukin-2 (IL-2).
Grouped product items
Size Price Stock Qty
5mg
$25.00
In stock
10mg
$25.00
In stock
25mg
$35.00
In stock
50mg
$40.00
In stock
100mg
$55.00
In stock
200mg
$100.00
In stock
500mg
$190.00
In stock
1g
$290.00
In stock
2g
$560.00
In stock
5g
$1,050.00
In stock
10mM * 1mL in DMSO
$35.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Adooq's Rapamycin (Sirolimus) has been cited by 18 publications
  • Saudatu Faruk, .et al. , J Trace Elem Med Biol, 2025, Sep 6:92:127740 PMID: 40945136
  • Saudatu Faruk, .et al. , Biol Trace Elem Res, 2025, May 8 PMID: 40338453
  • Saudat Faruk, .et al. , Iron, 2025, March
  • Yudong Li, .et al. , J Polym Sci, 2024, 62:2215-2230
  • Ross van de Weterin, .et al. , Glia, 2024, Jun 20 PMID: 38899723
  • Yuanqin Zhang, .et al. , Cancers (Basel), 2023, Dec 2;15(23):5691 PMID: 38067394
  • Amnon Wittenstein, .et al. , PLoS Biol, 2023, Nov 9;21(11):e3002355 PMID: 37943958
  • Bopei Cui, .et al. , Signal Transduct Target Ther, 2023, Sep 25;8(1):366 PMID: 37743418
  • Hideki Kawasaki, .et al. , J Insect Physiol, 2023, Mar;145:104476 PMID: 36623750
  • R Mahalakshmi, .et al. , Mol Biol Rep, 2022, Jan;49(1):463-476 PMID: 34739690
  • Yusuke Murase, .et al. , Oncol Rep, 2022, Apr;47(4):61 PMID: 35088890
  • Zhichao Wu, .et al. , Cells, 2021, Oct 27;10(11):2912 PMID: 34831135
  • Matthew A Schaller, .et al. , JCI Insight, 2021, Sep 22;6(18):e148003 PMID: 34357881
  • Matthew A. Schaller, .et al. , bioRxiv, 2021, January 21
  • Ashley VanCleave, .et al. , Oncotarget, 2020, Jul 7; 11(27): 2597-2610 PMID: 32676162
  • Y Huang, .et al. , Experimental and Therapeutic Medicine, 2020, 20(2), 736-747 PMID: 32742319
  • Takuya Hirao, .et al. , Cancer Sci, 2018, Jan; 109(1): 121-131 PMID: 29121435
  • Ya-Hui Chen, .et al. , J Diabetes Res, 2016, 2016: 1828071 PMID: 28004006
Biological Activity
DescriptionRapamycin (Sirolimus) prevents activation of T cells and B-cells by inhibiting their response to interleukin-2 (IL-2).
Targets
TargetValue
Cell Research
Cell LineTypeValueDescriptionReferences
Product Information
Catalog NumA10782
FormulaC51H79NO13
Molecular Weight914.2
CAS Number53123-88-9
SMILESC[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)O)C)/C)O)OC)C)C)/C)OC
SynonymsRapamune
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO18 mg/mL (19.68 mM)
WaterInsoluble
EthanolInsoluble
In vivo2% DMSO+30% PEG 300+5% Tween 80+ddH2O4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM10.94 mL54.69 mL109.39 mL
0.5 mM2.19 mL10.94 mL21.88 mL
1 mM1.09 mL5.47 mL10.94 mL
5 mM0.22 mL1.09 mL2.19 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

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    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2