Rapamycin (Sirolimus)

Catalog No.: A10782

mTOR Inhibitors

Rapamycin (Sirolimus)

Rapamycin (Sirolimus) Chemical Structure

CAS NO. 53123-88-9

Rapamycin (Sirolimus) prevents activation of T cells and B-cells by inhibiting their response to interleukin-2 (IL-2).

Availability: In stock

Package Price Qty
5 mg

Regular Price: $40.00

Special Price $32.00

25 mg

Regular Price: $120.00

Special Price $96.00

50 mg

Regular Price: $200.00

Special Price $160.00

100 mg

Regular Price: $350.00

Special Price $280.00

10mM * 1mL in DMSO
$132.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

Rapamycin (Sirolimus) prevents activation of T cells and B-cells by inhibiting their response to interleukin-2 (IL-2).
Targets
mTOR (HEK293 cells)
~0.1 nM
In vitro (25°C) DMSO 20 mg/mL (21.87 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% CMC/0.25% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 10.94 mL 54.69 mL 109.39 mL
0.5 mM 2.19 mL 10.94 mL 21.88 mL
1 mM 1.09 mL 5.47 mL 10.94 mL
5 mM 0.22 mL 1.09 mL 2.19 mL

*The above data is based on the productmolecular weight 914.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A10782
Actions Inhibitor
M. Wt 914.2
Formula C51H79NO13
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 53123-88-9
Synonyms Rapamune
SMILES C[[email protected]@H]1CC[[email protected]]2C[[email protected]@H](/C(=C/C=C/C=C/[[email protected]](C[[email protected]](C(=O)[[email protected]@H]([[email protected]@H](/C(=C/[[email protected]](C(=O)C[[email protected]](OC(=O)[[email protected]@H]3CCCCN3C(=O)C(=O)[[email protected]@]1(O2)O)[[email protected]](C)C[[email protected]@H]4CC[[email protected]]([[email protected]@H](C4)OC)O)C)/C)O)OC)C)C)/C)OC

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