Razaxaban hydrochloride is a selective and potent inhibitor of factor Xa, exhibiting a Ki of 0.19 nM. With over 5000-fold selectivity for factor Xa compared to other serine proteases, this compound effectively impedes the coagulation cascade. Additionally, Razaxaban hydrochloride displays thrombin inhibition with a Ki value of 540 nM, underscoring its significant antithrombotic properties. It is a valuable tool for research into anticoagulation therapies and the modulation of thrombotic disorders.
Razaxaban hydrochloride is a selective and potent inhibitor of factor Xa, exhibiting a Ki of 0.19 nM. With over 5000-fold selectivity for factor Xa compared to other serine proteases, this compound effectively impedes the coagulation cascade. Additionally, Razaxaban hydrochloride displays thrombin inhibition with a Ki value of 540 nM, underscoring its significant antithrombotic properties. It is a valuable tool for research into anticoagulation therapies and the modulation of thrombotic disorders.
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