Regorafénib N-oxyde-d3(M2) is a deuterium-labeled analog of Regorafénib N-oxyde M2, an active metabolite of the multi-targeted inhibitor Regorafenib. This compound targets key receptors including VEGFR1/2/3, PDGFRβ, Kit, RET, and Raf-1, exhibiting IC50 values of 13, 4.2, 46, 22, 7, 1.5, and 2.5 nM, respectively. Regorafénib N-oxyde-d3(M2) is primarily utilized in stable isotope labeling studies to trace metabolic pathways and explore pharmacokinetics in research applications.
Regorafénib N-oxyde-d3(M2) is a deuterium-labeled analog of Regorafénib N-oxyde M2, an active metabolite of the multi-targeted inhibitor Regorafenib. This compound targets key receptors including VEGFR1/2/3, PDGFRβ, Kit, RET, and Raf-1, exhibiting IC50 values of 13, 4.2, 46, 22, 7, 1.5, and 2.5 nM, respectively. Regorafénib N-oxyde-d3(M2) is primarily utilized in stable isotope labeling studies to trace metabolic pathways and explore pharmacokinetics in research applications.
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