Signaling Pathway
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| Discription | Remdesivir, also known as GS-5734, inhibits murine hepatitis virus (MHV) with an EC50 of 30 nM, and blocks SARS-CoV and MERS-CoV in HAE cells with EC50s of both 74 nM in HAE cells after treatment for 24 h. |
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| Catalog Num | A17170 |
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| Formula | C27H35N6O8P |
| Molecular Weight | 602.58 |
| CAS Number | 1809249-37-3 |
| SMILES | CCC(CC)COC([C@H](C)N[P@](OC[C@H]1O[C@](C2=CC=C3N2N=CC=C3N)(C#N)[C@H](O)[C@@H]1O)(OC4=CC=CC=C4)=O)=O |
| Synonyms | GS-5734, GS 5734, GS5734 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 96 mg/mL (159.31 mM) | |
| Water | Insoluble | ||
| Ethanol | 15 mg/mL | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.6 mL | 82.98 mL | 165.95 mL |
| 0.5 mM | 3.32 mL | 16.6 mL | 33.19 mL |
| 1 mM | 1.66 mL | 8.3 mL | 16.6 mL |
| 5 mM | 0.33 mL | 1.66 mL | 3.32 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
