Rhosin

Catalog No.: A21504

RhoA subfamily Rho GTPases inhibitor

Rhosin

Rhosin Chemical Structure

CAS NO. 1173671-63-0

Rhosin is a potent, specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction with a Kd of ~ 0.4 uM, and does not interact with Cdc42 or Rac1, nor the GEF, LARG. Rhosin induces cell apoptosis.

Availability: In stock

Package Price Qty
5 mg
$378.00
10 mg
$651.00
50 mg
$1,932.00
100 mg
$3,864.00
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Biological Activity

Rhosin is a potent, specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction with a Kd of ~ 0.4 uM, and does not interact with Cdc42 or Rac1, nor the GEF, LARG. Rhosin induces cell apoptosis.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.9 mL 139.51 mL 279.02 mL
0.5 mM 5.58 mL 27.9 mL 55.8 mL
1 mM 2.79 mL 13.95 mL 27.9 mL
5 mM 0.56 mL 2.79 mL 5.58 mL

*The above data is based on the productmolecular weight 358.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21504
Actions Inhibitor
M. Wt 358.4
Formula C20H18N6O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1173671-63-0
SMILES O=C(N/N=C/C1=CC=C2N=CC=NC2=C1)[[email protected]](N)CC3=CNC4=C3C=CC=C4

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