Riddelline is a pyrrolizidine alkaloid that functions as a potent inhibitor of DNA and RNA synthesis. It exhibits significant genotoxic properties by inducing elevations in unscheduled DNA synthesis and S-phase synthesis in rat liver models. This compound is utilized in research to study the mechanisms of genotoxicity and its implications in cellular processes and carcinogenesis.
Riddelline is a pyrrolizidine alkaloid that functions as a potent inhibitor of DNA and RNA synthesis. It exhibits significant genotoxic properties by inducing elevations in unscheduled DNA synthesis and S-phase synthesis in rat liver models. This compound is utilized in research to study the mechanisms of genotoxicity and its implications in cellular processes and carcinogenesis.
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