Ritolukast is a potent antagonist of the LTD4/E4 leukotriene receptors. This compound demonstrates significant biological activity by inhibiting bronchoconstriction induced by aerosolized LTD4, with an ID50 of 0.5 mg/kg in guinea pigs. Ritolukast is primarily utilized in research applications related to respiratory pharmacology and the study of allergic inflammatory responses.
Ritolukast is a potent antagonist of the LTD4/E4 leukotriene receptors. This compound demonstrates significant biological activity by inhibiting bronchoconstriction induced by aerosolized LTD4, with an ID50 of 0.5 mg/kg in guinea pigs. Ritolukast is primarily utilized in research applications related to respiratory pharmacology and the study of allergic inflammatory responses.
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