Ro-51 is a selective antagonist of the P2X3 and P2X2/3 receptors, demonstrating IC50 values of 2 nM and 5 nM, respectively. This compound effectively inhibits ATP-mediated signaling through these receptors, making it a valuable tool in pain research. Its specificity and potency allow for detailed investigations into the role of purinergic signaling in nociception and associated pain pathways.
Ro-51 is a selective antagonist of the P2X3 and P2X2/3 receptors, demonstrating IC50 values of 2 nM and 5 nM, respectively. This compound effectively inhibits ATP-mediated signaling through these receptors, making it a valuable tool in pain research. Its specificity and potency allow for detailed investigations into the role of purinergic signaling in nociception and associated pain pathways.
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