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RO4987655

MEK1 inhibitor

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Catalog No. A13272

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
RO4987655 5mg A13272-5
€209.00
RO4987655 10mg A13272-10
€361.00
RO4987655 25mg A13272-25
€665.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

RO4987655 is an orally active small molecule, targeting mitogen-activated protein kinase kinase 1 (MAP2K1 or MEK1), with potential antineoplastic activity.

RO4987655

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Chemical Information

Catalog Num A13272
Actions Inhibitor
M. Wt 565.28
Formula C20H19F3IN3O5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 874101-00-5
Synonyms RO-4987655, RO 4987655
SMILES code C1CC(=O)N(OC1)CC2=C(C(=C(C(=C2)C(=O)NOCCO)NC3=C(C=C(C=C3)I)F)F)F
Chemical Name 3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)-N-(2-hydroxyethoxy)-5-((3-oxo-1,2-oxazinan-2-yl)methyl)benzamide

Biological Activity

Description
 RO4987655 is an orally active small molecule, targeting mitogen-activated protein kinase kinase 1 (MAP2K1 or MEK1), with potential antineoplastic activity.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.69 mL 88.45 mL 176.9mL
0.5 mM 3.54 mL 17.69 mL 35.38 mL
1 mM 1.77 mL 8.85 mL 17.69 mL
5 mM 0.35 mL 1.77 mL 3.54 mL

*The above data is based on the productmolecular weight 565.28. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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