ROC-325

Catalog No.: A17031

Autophagy inhibitor

ROC-325

ROC-325 Chemical Structure

CAS NO. 1859141-26-6

ROC-325 is an autophagy inhibitor. ROC-325 exhibited superior in vitro anticancer effects compared with the existing autophagy inhibitor hydroxychloroquine (HCQ) in 12 different cancer cell lines with diverse genetic backgrounds.

Availability: In stock

Package Price Qty
5 mg
$120.00
10 mg
$180.00
50 mg
$580.00
100 mg
$980.00
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Biological Activity

ROC-325 is an autophagy inhibitor. ROC-325 exhibited superior in vitro anticancer effects compared with the existing autophagy inhibitor hydroxychloroquine (HCQ) in 12 different cancer cell lines with diverse genetic backgrounds.
In vitro DMSO 3 mg/mL (5.96 mM)
Water Insoluble
Ethanol 3 mg/mL (5.96 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.88 mL 99.39 mL 198.78 mL
0.5 mM 3.98 mL 19.88 mL 39.76 mL
1 mM 1.99 mL 9.94 mL 19.88 mL
5 mM 0.4 mL 1.99 mL 3.98 mL

*The above data is based on the productmolecular weight 503.06. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17031
Actions Inhibitor
CAS No. 1859141-26-6
Formula C28H27ClN4OS
M. Wt 503.06
Purity >98%
Synonyms ROC 325, ROC325
SMILES O=C1C2=C(C(C)=CC=C2NCCN(C)CCNC3=C(C=CC(Cl)=C4)C4=NC=C3)SC5=CC=CC=C51
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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