ROCK-IN-1

Catalog No.: A36816
ROCK Inhibitor
ROCK-IN-1 is a highly selective inhibitor of Rho-associated protein kinase (ROCK), demonstrating an IC50 of 1.2 nM specifically for ROCK2. This compound is valuable for studying the role of ROCK in cellular processes such as cytoskeletal dynamics, apoptosis, and smooth muscle contraction. ROCK-IN-1 is particularly useful in investigations related to cardiovascular diseases, cancer research, and neurological disorders.
Grouped product items
Size Price Stock Qty
1mg
$95.00
In stock
5mg
$235.00
In stock
10mg
$505.00
In stock
25mg
$1,050.00
In stock
50mg
$1,600.00
In stock
100mg
$2,560.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionROCK-IN-1 is a highly selective inhibitor of Rho-associated protein kinase (ROCK), demonstrating an IC50 of 1.2 nM specifically for ROCK2. This compound is valuable for studying the role of ROCK in cellular processes such as cytoskeletal dynamics, apoptosis, and smooth muscle contraction. ROCK-IN-1 is particularly useful in investigations related to cardiovascular diseases, cancer research, and neurological disorders.
Product Information
Catalog NumA36816
FormulaC20H18FN3O
Molecular Weight335.37
CAS Number934387-35-6
SMILESO=C(C1=CC(C2=CC=C(F)C=C2)=C(C(N)C)C=C1)NC3=CC=NC=C3
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