Roflupram is a selective phosphodiesterase 4 (PDE4) inhibitor that demonstrates oral bioavailability and effective central nervous system penetration, with an IC50 of 26.2 nM for human PDE4 core catalytic domains. This compound has been shown to reverse cognitive deficits and decrease the production of pro-inflammatory factors, making it valuable for research applications targeting neurological conditions and inflammation-related pathways.
Roflupram is a selective phosphodiesterase 4 (PDE4) inhibitor that demonstrates oral bioavailability and effective central nervous system penetration, with an IC50 of 26.2 nM for human PDE4 core catalytic domains. This compound has been shown to reverse cognitive deficits and decrease the production of pro-inflammatory factors, making it valuable for research applications targeting neurological conditions and inflammation-related pathways.
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