Rolapitant

Catalog No.: A13680

NK1 receptor antagonist

Rolapitant Chemical Structure

CAS NO. 552292-08-7

Rolapitant, also known as SCH-619734, is a selective, bioavailable, CNS penetrant neurokinin NK1 receptor antagonist that shows behavioral effects in animals models of emesis.

Availability: In stock

Package Price Qty
5 mg
$120.00
10 mg
$190.00
25 mg
$350.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Rolapitant, also known as SCH-619734, is a selective, bioavailable, CNS penetrant neurokinin NK1 receptor antagonist that shows behavioral effects in animals models of emesis.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.62 mL 93.12 mL 186.24 mL
0.5 mM 3.72 mL 18.62 mL 37.25 mL
1 mM 1.86 mL 9.31 mL 18.62 mL
5 mM 0.37 mL 1.86 mL 3.72 mL

*The above data is based on the productmolecular weight 536.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13680
Actions Antagonist
M. Wt 536.94
Formula C25H27ClF6N2O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 552292-08-7
Synonyms SCH619734, SCH-619734, SCH 619734
SMILES C[[email protected]](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)OC[[email protected]]2(CC[[email protected]]3(CCC(=O)N3)CN2)C4=CC=CC=C4

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