Ropinirole-d3 hydrochloride is a deuterium-labeled derivative of Ropinirole hydrochloride, functioning as a potent agonist for D2 and D3 dopamine receptors, with a Ki value of 29 nM for the D2 receptor. It exhibits pEC50 values of 7.4, 8.4, and 6.8 for human D2, D3, and D4 receptors, respectively, while showing no affinity for D1 receptors. This compound is primarily utilized in research related to dopamine receptor signaling and has potential implications for therapies targeting Parkinson's disease.
Ropinirole-d3 hydrochloride is a deuterium-labeled derivative of Ropinirole hydrochloride, functioning as a potent agonist for D2 and D3 dopamine receptors, with a Ki value of 29 nM for the D2 receptor. It exhibits pEC50 values of 7.4, 8.4, and 6.8 for human D2, D3, and D4 receptors, respectively, while showing no affinity for D1 receptors. This compound is primarily utilized in research related to dopamine receptor signaling and has potential implications for therapies targeting Parkinson's disease.
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