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Ropinirole-d3 hydrochloride

Stable Isotope

Ropinirole-d3 hydrochloride is a deuterium-labeled derivative of Ropinirole hydrochloride, functioning as a potent agonist for D2 and D3 dopamine receptors, with a Ki value of 29 nM for the D2 receptor. It exhibits pEC50 values of 7.4, 8.4, and 6.8 for human D2, D3, and D4 receptors, respectively, while showing no affinity for D1 receptors. This compound is primarily utilized in research related to dopamine receptor signaling and has potential implications for therapies targeting Parkinson's disease.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1329611-00-8
Applications	Stable Isotope
Formula	C₁₆H₂₂D₃ClN₂O
Molecular Weight	299.85
Synonyms	SKF 101468-d3 hydrochloride
SMILES	[2H]C([2H])([2H])CCN(CCC)CCC1=C2C(NC(C2)=O)=CC=C1.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.