ROR agonist-1

Catalog No.: A18569

ROR agonist

ROR agonist-1

ROR agonist-1 Chemical Structure

CAS NO. 2361528-74-5

ROR agonist-1 is a potent and orally bioavailable inverse agonist of the retinoic acid receptor-related orphan receptor C2 (RORC2), inhibition of IL-17A production from human primary TH 17 cells with a pIC50 of 7.5.

Availability: In stock

Package Price Qty
1 mg

Regular Price: $320.00

Special Price $256.00

5 mg

Regular Price: $960.00

Special Price $768.00

10 mg

Regular Price: $1,600.00

Special Price $1,280.00

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Biological Activity

ROR agonist-1 is a potent and orally bioavailable inverse agonist of the retinoic acid receptor-related orphan receptor C2 (RORC2), inhibition of IL-17A production from human primary TH 17 cells with a pIC50 of 7.5.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19 mL 94.98 mL 189.95 mL
0.5 mM 3.8 mL 19 mL 37.99 mL
1 mM 1.9 mL 9.5 mL 19 mL
5 mM 0.38 mL 1.9 mL 3.8 mL

*The above data is based on the productmolecular weight 526.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18569
Actions Agonist
CAS No. 2361528-74-5
Formula C21H20F6N2O5S
M. Wt 526.45
Purity >98%
SMILES O=C([[email protected]](NC(C)=O)C1=CC=C(S(=O)(CC)=O)C=C1)NC2=CC=C(C(O)(C(F)(F)F)C(F)(F)F)C=C2
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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