Rosuvastatin calcium (Crestor)

Catalog No.: A10810

HMG-CoA reductase inhibitor

Rosuvastatin calcium (Crestor)

Rosuvastatin calcium (Crestor) Chemical Structure

CAS NO. 147098-20-2

Rosuvastatin (Crestor) is a member of the drug class of statins, used to treat high cholesterol and related conditions, and to prevent cardiovascular disease. Rosuvastatin is a competitive inhibitor of the enzyme HMG-CoA reductase, having a mechanism of action similar to that of other statins.

Availability: In stock

Package Price Qty
25 mg
$50.00
50 mg
$70.00
100 mg
$90.00
200 mg
$120.00
10mM * 1mL in DMSO
$55.00
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Biological Activity

Rosuvastatin (Crestor) is a member of the drug class of statins, used to treat high cholesterol and related conditions, and to prevent cardiovascular disease. Rosuvastatin is a competitive inhibitor of the enzyme HMG-CoA reductase, having a mechanism of action similar to that of other statins.
In vitro (25°C) DMSO Warmed: 91 mg/mL (181.79 mM)
Water Insoluble
Ethanol Insoluble
In vivo 4% DMSO+30% PEG 300+dd H2O 9 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.94 mL 99.7 mL 199.4 mL
0.5 mM 3.99 mL 19.94 mL 39.88 mL
1 mM 1.99 mL 9.97 mL 19.94 mL
5 mM 0.4 mL 1.99 mL 3.99 mL

*The above data is based on the productmolecular weight 501.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10810
Actions Inhibitor
CAS No. 147098-20-2
Formula C22H28FN3O6S.1/2Ca
M. Wt 501.5
Purity >98%
SMILES CC(C1=NC(=NC(=C1/C=C/[[email protected]@H](O)C[[email protected]@H](O)CC(=O)[O-])C2=CC=C(C=C2)F)N(S(=O)(=O)C)C)C.CC(C1=NC(=NC(=C1/C=C/[[email protected]@H](O)C[[email protected]@H](O)CC(=O)[O-])C2=CC=C(C=C2)F)N(S(=O)(=O)C)C)C.[Ca+2]
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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