RPR 130737 is a selective and potent competitive inhibitor of Factor Xa, exhibiting an inhibition constant (Ki) of 2.4 nM. This compound demonstrates over 1000-fold selectivity against thrombin, activated protein C, plasmin, tissue-plasminogen activator, and trypsin, making it an ideal tool for cardiovascular research. RPR 130737 effectively prolongs both activated partial thromboplastin time and prothrombin time while having no impact on platelet aggregation. It is primarily utilized in studies relating to thrombotic disorders and cardiovascular diseases.
RPR 130737 is a selective and potent competitive inhibitor of Factor Xa, exhibiting an inhibition constant (Ki) of 2.4 nM. This compound demonstrates over 1000-fold selectivity against thrombin, activated protein C, plasmin, tissue-plasminogen activator, and trypsin, making it an ideal tool for cardiovascular research. RPR 130737 effectively prolongs both activated partial thromboplastin time and prothrombin time while having no impact on platelet aggregation. It is primarily utilized in studies relating to thrombotic disorders and cardiovascular diseases.
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