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Biological Activity
RPR107393 free base is a selective squalene synthase inhibitor, which inhibits rat liver microsomal squalene synthase with an IC50 of 0.8??0.2 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.26 mL | 151.32 mL | 302.65 mL |
| 0.5 mM | 6.05 mL | 30.26 mL | 60.53 mL |
| 1 mM | 3.03 mL | 15.13 mL | 30.26 mL |
| 5 mM | 0.61 mL | 3.03 mL | 6.05 mL |
*The above data is based on the productmolecular weight 330.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13051 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 197576-78-6 |
| Formula | C22H22N2O |
| M. Wt | 330.42 |
| Purity | >98% |
| Synonyms | RPR 107393, RPR-107393 |
| SMILES | OC1(C2=CC=C(C3=CC=C4N=CC=CC4=C3)C=C2)CN5CCC1CC5 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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