RTI-122 is a potent agonist of the GPR88 receptor, demonstrating effective brain penetration and a half-life of 5.8 hours in murine models. This compound exhibits a cAMP EC50 value of 11 nM, making it a valuable tool for investigating mechanisms associated with excessive drinking behaviors. Its metabolic stability and selective activity position RTI-122 as a significant reagent for research in addiction neuroscience and related fields.
RTI-122 is a potent agonist of the GPR88 receptor, demonstrating effective brain penetration and a half-life of 5.8 hours in murine models. This compound exhibits a cAMP EC50 value of 11 nM, making it a valuable tool for investigating mechanisms associated with excessive drinking behaviors. Its metabolic stability and selective activity position RTI-122 as a significant reagent for research in addiction neuroscience and related fields.
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