You have no items in your shopping cart.
Publications citing Adooq Products
Chemical Information
| Catalog Num | A13552 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 425.49736 |
| Formula | C27H24FN3O |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 215303-72-3 |
| Synonyms | RWJ 67657, RWJ67657 |
| SMILES | C1=CC=C(C=C1)CCCN2C(=NC(=C2C3=CC=NC=C3)C4=CC=C(C=C4)F)C#CCCO |
Description |
RWJ-67657 is a potent p38 MAPK inhibitor. | |||||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.5 mL | 117.51 mL | 235.02mL |
| 0.5 mM | 4.7 mL | 23.5 mL | 47 mL |
| 1 mM | 2.35 mL | 11.75 mL | 23.5 mL |
| 5 mM | 0.47 mL | 2.35 mL | 4.7 mL |
*The above data is based on the productmolecular weight 425.49736. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Ordering online
To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.
To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.
When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards. We will then liaise with you or your purchasing department to confirm the order.
Found your products but not ready to order?
Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.
Ordering offline
You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order. Our contact details are:
- Tel: 866-930-6790
- Fax: 323-606-8156
- Email: [email protected]
We require the following information to process your order:
- The catalog number for each product.
- Your email address or fax number.
- Your name and telephone number.
- Shipping address and billing address.
- Purchase order numbers.
Similar product(s)
Special Price Starting at:
$45.00
SB 203580 is a specific inhibitor of p38α and p38β which suppresses downstream activation of MAPKAP kinase-2 and heat shock protein 27.
...
Special Price Starting at: $45.00
Special Price Starting at:
$150.00
SB-242235 is a potent and selective p38 MAP kinase inhibitor that may be an effective therapy for cytokine-mediated diseases such as autoimmune or inflammatory diseases. ...
Special Price Starting at: $150.00
Special Price Starting at:
$71.10
Asiatic acid is commonly used in wound healing. Asiatic acid has antioxidant, anti-inflammatory and neuroprotective properties. Asiatic acid derivative synthesis can be ...
Special Price Starting at: $71.10
Asiatic acid is commonly used in wound healing. Asiatic acid has antioxidant, anti-inflammatory and neuroprotective properties. Asiatic acid derivative synthesis can be ...
Special Price Starting at:
$350.00
SD-06 is a p38 MAP kinase inhibitor; inhibits p38α with an IC50 value of 170 nM and inhibits LPS-stimulated TNF-release in rats (83% inhibition at 1mg/kg, po). ...
Special Price Starting at: $350.00
Special Price Starting at:
$150.00
Talmapimod (SCIO-469) is a selective, ATP-competitive p38 inhibitor (IC50 = 9 nM for p38α in vitro).
...
Special Price Starting at: $150.00
Special Price Starting at:
$140.00
DBM 1285 dihydrochloride is a p38 MAPK inhibitor. Supresses p38 phosphorylation and LPS-induced TNF-α production in macrophages and in vivo. ...
Special Price Starting at: $140.00
Special Price Starting at:
$54.00
VX-745 is a small-molecule inhibitor of MAPK that is reported to be active against several isotypes of p38 MAPK, including p38α, p38βand p38γ .
...
Special Price Starting at: $54.00
Special Price Starting at:
$150.00
AMG 548 is a potent and selective inhibitor of p38α. It displays >1000-fold selectivity against 36 other kinases, and it inhibits whole blood LPS-stimulated TNFα. ...
Special Price Starting at: $150.00
Special Price Starting at:
$54.00
SB 239063 is a potent and selective p38 MAP kinase inhibitor (IC50 = 44 nM for p38α). SB 239063 displays > 220-fold selectivity over ERK, JNK1 and other kinases; ~ 3-fold more selective than SB 20358 ...
Special Price Starting at: $54.00
Special Price Starting at:
$140.00
TRC 051384, belonging to substituted 2-propen-1-one class, is a potent inducer of heat shock protein 70 (HSP70) [1]. Induction of HSP70 is a natural response of stressed cells that protects neuronal c ...
Special Price Starting at: $140.00
Special Price Starting at:
$81.00
LY2228820 is a novel and potent p38MAPK inhibitor with potent antiinflammatory activity. ...
Special Price Starting at: $81.00
Special Price Starting at:
$250.00
BMS-582949 Is a Dual Action p38 Kinase Inhibitor Well Suited To Avoid Resistance Mechanisms That Increase p38 Activation in Cells. ...
Special Price Starting at: $250.00
Special Price Starting at:
$108.00
Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor. ...
Special Price Starting at: $108.00
Special Price Starting at:
$120.00
EO 1428 is a synthetic 4-aminobenzophenone small molecule identified in an optimization study for inhibitors of p38 MAP kinase. ...
Special Price Starting at: $120.00
Special Price Starting at:
$27.00
Doramapimod (BIRB 796) is a small molecule inhibitor of p38 MAPK,which plays a critical role in regulating the production of proinflammatory cytokines. ...
Special Price Starting at: $27.00
Special Price Starting at:
$350.00
Pamapimod is a novel p38 mitogen-activated protein kinase inhibitor. ...
Special Price Starting at: $350.00
Special Price Starting at:
$54.00
Vinorelbine is the first 5´NOR semi-synthetic vinca alkaloid. It is obtained by semi-synthesis from alkaloids extracted from the rosy periwinkle, Catharanthus roseus. ...
Special Price Starting at: $54.00
Special Price Starting at:
$140.00
AL-8697 is a selective p38 MAPK(mitogen-activated protein Kinase) inhibitor, which is also named P38α inhibitor. It has the function of inhibiting the activity of P38 MAPK. ...
Special Price Starting at: $140.00
Special Price Starting at:
$120.00
ML-3043 is a p38 MAPK inhibitor (IC50 = 0.38 μM). Inhibits the release of IL-1β and TNF-α in a peripheral blood mononuclear cell (PBMC) assay (IC50 values are 0.039 and 0.16 μM respectively).
...
Special Price Starting at: $120.00
Special Price Starting at:
$110.00
PH-797804 is a diarylpyridinone inhibitor of p38 mitogen-activated protein (MAP) kinase. ...
Special Price Starting at: $110.00
Special Price Starting at:
$100.00
SKF 86002 Dihydrochloride is inhibitor of p38 MAP kinase (IC50 = 0.1 - 1 uM). Potently inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50 = 1 uM). ...
Special Price Starting at: $100.00
Special Price Starting at:
$72.00
TAK 715 an inhibitor of p38 MAPK (IC50 = 7.1 nM for p38 MAPKα), Wnt/beta-catenin signaling, and Inhibits 22 kinases by more than 80%, including CK 1δ/ε. ...
Special Price Starting at: $72.00
Special Price Starting at:
$140.00
SB 706504 is a p38 MAPK inhibitor, preventing LPS-induced transcription of a range of chemokineis and cytokines in chronic obstructive pulmonary disease monocyte derived macrophages. ...
Special Price Starting at: $140.00
Special Price Starting at:
$36.00
VX-702 is an orally bioavailable inhibitor of p38 MAP kinase that inhibits platelet agonist induced p38 activation (IC50= 4 to 20 nM). ...
Special Price Starting at: $36.00
Special Price Starting at:
$90.00
Pexmetinib is a potent inhibitor of cytokine synthesis, via the dual inhibition of p38 mitogen-activated protein kinase (MAPK), and Tie2/Tek receptor tyrosine kinase. ...
Special Price Starting at: $90.00
Special Price Starting at:
$27.00
Asiaticoside (Madecassol) is the active chemical component of the plant Centella asiatica. Asiaticoside is used to study potential treatments for wounds and burns. ...
Special Price Starting at: $27.00
Special Price Starting at:
$120.00
JX 401 is a potent, reversible inhibitor of the p38α isoform of MAP kinase (IC50 = 32 nM). ...
Special Price Starting at: $120.00
Special Price Starting at:
$36.00
SB202190 is a highly selective, potent and cell-permeable inhibitor of p38 MAP kinase. ...
Special Price Starting at: $36.00
Special Price Starting at:
$1,850.00
Dilmapimod is p38 MAPK inhibitor. ...
Special Price Starting at: $1,850.00
Special Price Starting at:
$45.00
PD 169316 (PD169316) is a selective inhibitor of p38 MAPK.1 that inhibits p38 MAPK with an IC50 of 89 nM. ...
Special Price Starting at: $45.00
Keywords:buy RWJ-67657 | RWJ-67657 Supplier | purchase RWJ-67657 | RWJ-67657 cost | RWJ-67657 manufacturer | order RWJ-67657 | RWJ-67657 distributor | buy 215303-72-3| 215303-72-3 Supplier | purchase 215303-72-3 | 215303-72-3 cost | 215303-72-3 manufacturer | order 215303-72-3 | 215303-72-3 distributor
We Using Safe Payments:
