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(S)-10-Hydroxycamptothecin

Catalog No.: A11997
Topoisomerase
(S)-10-Hydroxycamptothecin is a camptothecin derivative that inhibits DNA topoisomerase by enacting strand breaks in chromosomal DNA and inducing apoptosis.
(S)-10-Hydroxycamptothecin
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Product Name Price Stock Qty
(S)-10-Hydroxycamptothecin 50mg
Special Price $48.00 Regular Price $60.00
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(S)-10-Hydroxycamptothecin 100mg
Special Price $80.00 Regular Price $100.00
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(S)-10-Hydroxycamptothecin 250mg
Special Price $160.00 Regular Price $200.00
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(S)-10-Hydroxycamptothecin 500mg
Special Price $280.00 Regular Price $350.00
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(S)-10-Hydroxycamptothecin 10mM * 1mL in DMSO
Special Price $50.40 Regular Price $63.00
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Biological Activity
Discription (S)-10-Hydroxycamptothecin is a camptothecin derivative that inhibits DNA topoisomerase by enacting strand breaks in chromosomal DNA and inducing apoptosis.
Targets
Target Value
Product Information
Catalog Num A11997
Formula C20H16N2O5
Molecular Weight 364.35
CAS Number 19685-09-7
SMILES CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=CC5=C4)O)O
Synonyms HCPT;SN38;Ampule;NSC 107124;HYDROCAMPTOTHECINE;HYDROXYCAMPTOTHECIN;
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Solubility
In vitro (25°C) DMSO Warmed: 7 mg/mL (19.21 mM)
Water Insoluble
Ethanol Insoluble
In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.45 mL 137.23 mL 274.46 mL
0.5 mM 5.49 mL 27.45 mL 54.89 mL
1 mM 2.74 mL 13.72 mL 27.45 mL
5 mM 0.55 mL 2.74 mL 5.49 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Natural Products
DNA Damage > Topoisomerase
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