(S)-10-Hydroxycamptothecin

Catalog No.: A11997

Topoisomerase

(S)-10-Hydroxycamptothecin

(S)-10-Hydroxycamptothecin Chemical Structure

CAS NO. 19685-09-7

(S)-10-Hydroxycamptothecin is a camptothecin derivative that inhibits DNA topoisomerase by enacting strand breaks in chromosomal DNA and inducing apoptosis.

Availability: In stock

Package Price Qty
50 mg

Regular Price: $60.00

Special Price $54.00

100 mg

Regular Price: $100.00

Special Price $90.00

250 mg

Regular Price: $200.00

Special Price $180.00

500 mg

Regular Price: $350.00

Special Price $315.00

10mM * 1mL in DMSO

Regular Price: $63.00

Special Price $56.70

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

(S)-10-Hydroxycamptothecin is a camptothecin derivative that inhibits DNA topoisomerase by enacting strand breaks in chromosomal DNA and inducing apoptosis.
Targets
DNA topoisomerase I
In vitro (25°C) DMSO 8 mg/mL heating (21.95 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.45 mL 137.23 mL 274.46 mL
0.5 mM 5.49 mL 27.45 mL 54.89 mL
1 mM 2.74 mL 13.72 mL 27.45 mL
5 mM 0.55 mL 2.74 mL 5.49 mL

*The above data is based on the productmolecular weight 364.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A11997
Actions Inhibitor
M. Wt 364.35
Formula C20H16N2O5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 19685-09-7
Synonyms HCPT;SN38;Ampule;NSC 107124;HYDROCAMPTOTHECINE;HYDROXYCAMPTOTHECIN;
SMILES CC[[email protected]@]1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=CC5=C4)O)O

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy (S)-10-Hydroxycamptothecin | (S)-10-Hydroxycamptothecin Supplier | purchase (S)-10-Hydroxycamptothecin | (S)-10-Hydroxycamptothecin cost | (S)-10-Hydroxycamptothecin manufacturer | order (S)-10-Hydroxycamptothecin | (S)-10-Hydroxycamptothecin distributor | buy 19685-09-7| 19685-09-7 Supplier | purchase 19685-09-7 | 19685-09-7 cost | 19685-09-7 manufacturer | order 19685-09-7 | 19685-09-7 distributor
Rewards