(S)-JNJ-54166060

Catalog No.: A67915
P2X7 Antagonist
(S)-JNJ-54166060 is a selective P2X7 antagonist, exhibiting potent inhibitory activity against the P2X7 receptor. This compound is useful in research related to chronic inflammatory diseases, neurodegeneration, and pain pathways, as well as studying the role of P2X7 in immune responses. Its specificity and efficacy make it a valuable tool for investigating the therapeutic potential of modulating P2X7 signaling.
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5mg
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50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(S)-JNJ-54166060 is a selective P2X7 antagonist, exhibiting potent inhibitory activity against the P2X7 receptor. This compound is useful in research related to chronic inflammatory diseases, neurodegeneration, and pain pathways, as well as studying the role of P2X7 in immune responses. Its specificity and efficacy make it a valuable tool for investigating the therapeutic potential of modulating P2X7 signaling.
Product Information
Catalog NumA67915
FormulaC20H15ClF4N4O
Molecular Weight438.81
CAS Number1627900-42-8
SMILESO=C(C1=CC=CC(C(F)(F)F)=C1Cl)N2CCC3=C(N=CN3C4=NC=C(F)C=C4)[C@@H]2C
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