(S,R,S)-AHPC-C2-NH2 is an E3 ligase ligand-linker conjugate that incorporates the VH032-derived VHL ligand, designed for applications in targeted protein degradation via PROTAC technology. This compound facilitates the recruitment of E3 ligases to target proteins, enabling efficient ubiquitination and subsequent proteasomal degradation. Its use in research can enhance the understanding of protein dynamics and assist in the development of therapeutics aimed at regulating protein levels in various disease contexts.
(S,R,S)-AHPC-C2-NH2 is an E3 ligase ligand-linker conjugate that incorporates the VH032-derived VHL ligand, designed for applications in targeted protein degradation via PROTAC technology. This compound facilitates the recruitment of E3 ligases to target proteins, enabling efficient ubiquitination and subsequent proteasomal degradation. Its use in research can enhance the understanding of protein dynamics and assist in the development of therapeutics aimed at regulating protein levels in various disease contexts.
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