(S,R,S)-AHPC-C3-NH2 dihydrochloride is a synthesized E3 ligase ligand-linker conjugate, incorporating the VH032-based VHL ligand and a linker utilized in PROTAC (proteolysis-targeting chimera) technology. This compound serves as a critical building block in the synthesis of various PROTACs, including UNC6852, which is a bivalent chemical degrader specifically targeting EED. (S,R,S)-AHPC-C3-NH2 dihydrochloride facilitates investigations into targeted protein degradation, offering valuable insights into protein regulation and potential therapeutic strategies.
(S,R,S)-AHPC-C3-NH2 dihydrochloride is a synthesized E3 ligase ligand-linker conjugate, incorporating the VH032-based VHL ligand and a linker utilized in PROTAC (proteolysis-targeting chimera) technology. This compound serves as a critical building block in the synthesis of various PROTACs, including UNC6852, which is a bivalent chemical degrader specifically targeting EED. (S,R,S)-AHPC-C3-NH2 dihydrochloride facilitates investigations into targeted protein degradation, offering valuable insights into protein regulation and potential therapeutic strategies.
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