Fig. 1 · Structure
Documents & Downloads
(S,R,S)-AHPC-PEG2-acid
PROTAC Linkers
(S,R,S)-AHPC-PEG2-acid is a PEG-based linker designed for use in the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates targeted protein degradation by connecting an E3 ligase ligand to a target protein ligand. Its utilization in research allows for the investigation of protein degradation mechanisms and the development of novel therapeutic strategies in oncology and beyond.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2172820-09-4 |
| Applications | PROTAC Linkers |
| Formula | C30H42N4O8S |
| Molecular Weight | 618.74 |
| SMILES | O=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[C@H]3N(C([C@H](C(C)(C)C)NC(CCOCCOCCC(O)=O)=O)=O)C[C@H](O)C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.