(S,R,S)-AHPC-PEG5-Boc

Catalog No.: A80014
E3 Ligase Ligand-Linker Conjugates
(S,R,S)-AHPC-PEG5-Boc is an E3 ligase ligand-linker conjugate designed for targeted protein degradation. This compound combines the (S,R,S)-AHPC variant of the VHL ligand with a polyethylene glycol (PEG) linker to facilitate the efficient ubiquitination of Cdc20. Its primary application lies in the development of targeted therapeutic strategies aimed at modulating protein levels within cellular systems. This compound is ideal for use in drug discovery research focusing on E3 ligase-mediated degradation.
Grouped product items
Size Price Stock Qty
5mg
$55.00
In stock
10mg
$90.00
In stock
25mg
$185.00
In stock
50mg
$285.00
In stock
100mg
$450.00
In stock
250mg
$740.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(S,R,S)-AHPC-PEG5-Boc is an E3 ligase ligand-linker conjugate designed for targeted protein degradation. This compound combines the (S,R,S)-AHPC variant of the VHL ligand with a polyethylene glycol (PEG) linker to facilitate the efficient ubiquitination of Cdc20. Its primary application lies in the development of targeted therapeutic strategies aimed at modulating protein levels within cellular systems. This compound is ideal for use in drug discovery research focusing on E3 ligase-mediated degradation.
Product Information
Catalog NumA80014
FormulaC40H62N4O11S
Molecular Weight807.01
CAS Number2923734-82-9
SMILESCC(C)(C)[C@@H](C(N1C[C@@H](C[C@H]1C(NCC2=CC=C(C=C2)C3=C(N=CS3)C)=O)O)=O)NC(CCOCCOCCOCCOCCOCCC(OC(C)(C)C)=O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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