SAG

Catalog No.: A13627

SMO agonist

SAG Chemical Structure

CAS NO. 912545-86-9

SAG is a chlorobenzothiophene-containing compound which acts as a SMO agonist (EC50 = 3 nM) but inhibits hedgehog signaling at high concentrations (>1 uM).

Availability: In stock

Package Price Qty
2 mg
$70.00
5 mg
$110.00
10 mg
$170.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

SAG is a chlorobenzothiophene-containing compound which acts as a SMO agonist (EC50 = 3 nM) but inhibits hedgehog signaling at high concentrations (>1 uM).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.4 mL 102.02 mL 204.04 mL
0.5 mM 4.08 mL 20.4 mL 40.81 mL
1 mM 2.04 mL 10.2 mL 20.4 mL
5 mM 0.41 mL 2.04 mL 4.08 mL

*The above data is based on the productmolecular weight 490.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13627
Actions Agonist
M. Wt 490.1
Formula C28H28ClN3OS
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 912545-86-9
Synonyms Smoothened Agonist
SMILES CNC1CCC(CC1)N(CC2=CC=CC(=C2)C3=CC=NC=C3)C(=O)C4=C(C5=CC=CC=C5S4)Cl

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