Catalog No.: A14328

microtubule stabilizer


Sagopilone Chemical Structure

CAS NO. 305841-29-6

Sagopilone is a fully synthetic low-molecular-weight epothilone with potential antineoplastic activity.

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  • Payal Ranaa, .et al. Utilization of iPSC-derived human neurons for high-throughput drug-induced peripheral neuropathy screening, Toxicol In Vitro, 2017, Dec;45(Pt 1):111-118 PMID: 28843493

Biological Activity

Sagopilone is a fully synthetic low-molecular-weight epothilone with potential antineoplastic activity.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.39 mL 91.96 mL 183.92 mL
0.5 mM 3.68 mL 18.39 mL 36.78 mL
1 mM 1.84 mL 9.2 mL 18.39 mL
5 mM 0.37 mL 1.84 mL 3.68 mL

*The above data is based on the productmolecular weight 543.71. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14328
Actions Stabilizer
CAS No. 305841-29-6
Formula C30H41NO6S
M. Wt 543.71
Solubility DMSO
Purity >98%
Synonyms DE 03757, ZK 219477, ZK-EPO
SMILES C[[email protected]]1CCC[[email protected]@]2([[email protected]@H](O2)C[[email protected]](OC(=O)C[[email protected]@H](C(C(=O)[[email protected]@H]([[email protected]]1O)CC=C)(C)C)O)C3=CC4=C(C=C3)SC(=N4)C)C

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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