SAR-20347

Catalog No.: A20380
TYK2/JAK1/JAK2/JAK3 inhibitor
SAR-20347 is an inhibitor of TYK2, JAK1, JAK2 and JAK3 with IC50s of 0.6, 23, 26 and 41 nM, respectively.
Grouped product items
Product Name Price Stock Qty
SAR-20347 5mg
$130.00
In stock
SAR-20347 10mg
$223.00
In stock
SAR-20347 50mg
$662.00
In stock
SAR-20347 100mg
$1,325.00
In stock
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Bulk Discount
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Biological Activity
Discription SAR-20347 is an inhibitor of TYK2, JAK1, JAK2 and JAK3 with IC50s of 0.6, 23, 26 and 41 nM, respectively.
Targets
Target Value
Product Information
Catalog Num A20380
Formula C21H18ClFN4O4
Molecular Weight 444.84
CAS Number 1450881-55-6
SMILES O=C(C1=C(NC2=CC=C(C(N3CCOCC3)=O)C=C2)OC(C4=C(F)C=CC=C4Cl)=N1)N
Synonyms SAR20347, SAR 20347
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 77 mg/mL (173.09 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.48 mL 112.4 mL 224.8 mL
0.5 mM 4.5 mL 22.48 mL 44.96 mL
1 mM 2.25 mL 11.24 mL 22.48 mL
5 mM 0.45 mL 2.25 mL 4.5 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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