SAR-7334 HCl

Catalog No.: A17237

TRPC6 inhibitor

SAR-7334 HCl Chemical Structure

CAS NO. 1333207-63-8

SAR7334 is a novel, highly potent and bioavailable inhibitor of TRPC6 channels that opens new opportunities for the investigation of TRPC channel function in vivo. SAR7334 inhibited TRPC6, TRPC3 and TRPC7-mediated Ca(2+) influx into cells with IC50 s of 9.5, 282 and 226 nM, whereas TRPC4 and TRPC5-mediated Ca(2+) entry was not affected.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $300.00

Special Price $240.00

10 mg

Regular Price: $400.00

Special Price $320.00

50 mg

Regular Price: $720.00

Special Price $576.00

100 mg

Regular Price: $900.00

Special Price $720.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

SAR7334 is a novel, highly potent and bioavailable inhibitor of TRPC6 channels that opens new opportunities for the investigation of TRPC channel function in vivo. SAR7334 inhibited TRPC6, TRPC3 and TRPC7-mediated Ca(2+) influx into cells with IC50 s of 9.5, 282 and 226 nM, whereas TRPC4 and TRPC5-mediated Ca(2+) entry was not affected.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.69 mL 113.43 mL 226.86 mL
0.5 mM 4.54 mL 22.69 mL 45.37 mL
1 mM 2.27 mL 11.34 mL 22.69 mL
5 mM 0.45 mL 2.27 mL 4.54 mL

*The above data is based on the productmolecular weight 440.793. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17237
M. Wt 440.793
Formula C21H24Cl3N3O
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 1333207-63-8
Synonyms SAR-7334; SAR 7334; SAR7334
SMILES N#CC1=CC=C(O[[email protected]]2[[email protected]](N3C[[email protected]](N)CCC3)CC4=C2C=CC=C4)C(Cl)=C1.[H]Cl.[H]Cl

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