SAR156497

Catalog No.: A14382

Aurora Kinase inhibitor

SAR156497

SAR156497 Chemical Structure

CAS NO. 1256137-14-0

SAR156497 is an exquisitely selective Aurora A, B, and C inhibitor with in vitro and in vivo efficacy with IC50 = 0.5 nM (Aurora A), 1 nM (Aurora B / incenp), 3 nM (Aurora C / incenp) respectively SAR156497 combines high in vitro potency with satisfactory metabolic stability and limited CYP3A4 and PDE3 inhibition.

Availability: Out of stock

Package Price
5 mg

Regular Price: $350.00

Special Price $280.00

10 mg

Regular Price: $600.00

Special Price $480.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

SAR156497 is an exquisitely selective Aurora A, B, and C inhibitor with in vitro and in vivo efficacy with IC50 = 0.5 nM (Aurora A), 1 nM (Aurora B / incenp), 3 nM (Aurora C / incenp) respectively SAR156497 combines high in vitro potency with satisfactory metabolic stability and limited CYP3A4 and PDE3 inhibition.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.34 mL 106.72 mL 213.45 mL
0.5 mM 4.27 mL 21.34 mL 42.69 mL
1 mM 2.13 mL 10.67 mL 21.34 mL
5 mM 0.43 mL 2.13 mL 4.27 mL

*The above data is based on the productmolecular weight 468.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A14382
Actions Inhibitor
M. Wt 468.5
Formula C27H24N4O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1256137-14-0
Synonyms SAR-156497, SAR 156497
SMILES O=C(C1=C2NC3=C(C(CCC3)=O)[[email protected]@H](C4=CC=CC(OC5=NC6=CC=CC=C6N5)=C4)C2=CN1)OCC

Product Tags

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy SAR156497 | SAR156497 Supplier | purchase SAR156497 | SAR156497 cost | SAR156497 manufacturer | order SAR156497 | SAR156497 distributor | buy 1256137-14-0| 1256137-14-0 Supplier | purchase 1256137-14-0 | 1256137-14-0 cost | 1256137-14-0 manufacturer | order 1256137-14-0 | 1256137-14-0 distributor
Rewards